Invitation

WEBINAR

'Advancing in EVs Characterization'

Online TEAMS Weizmann Inst.

30

October

2025

Agenda:

Gathering & Coffee 
Lubin Building for Biological Sciences, Room 1
Weizmann Institute of Science
Rehovot, 76100, Israel

8:30 – 9:00

Welcoming & Introduction
Dr. Avi Dayan, Weizmann Inst. MULTIDISCIPLINARY VESICLE PROGRAM (MVP)

9:00 – 9:05

Advancing Nanoparticle Tracking Analysis (NTA): Simultaneous Multispectral Detection for Accurate Enumeration and Sizing
Julie Chen, HORIBA

9:05 – 10:20

Coffee Break

10:20 – 11:00

Perspectives of Interfacial Chemical Measurements in the Field of EVs studies.
Dr. Michaela Laupheimer, DataPhysics

11:00 – 11:45

Closing

11:50

Julie Y. Chen is the Particle Science Liaison at HORIBA and the founder of JCAnalysis, an analytical testing service based in Southern California specializing in nano-to-subvisible materials. She partners with key opinion leaders (KOLs), bridging the gap between HORIBA and prospective customers to drive growth and innovation. A University of California, Irvine graduate in Chemistry with a focus on Biochemistry, Julie brings nearly two decades of expertise in particle characterization, business development, collaborative studies, and emerging opportunities. Outside of work, she is a wife and proud mom of two young daughters

Abstract:
Advancing Nanoparticle Tracking Analysis (NTA): Simultaneous Multispectral Detection for Accurate Enumeration and Sizing
Nanoparticle Tracking Analysis (NTA) is increasingly essential as regulatory guidance on nanomaterials shift to number-based metrics. By visualizing and tracking the Brownian motion of individual particles, NTA delivers size and concentration for applications such as extracellular vesicles, microplastics, nanobubbles, protein aggregation or liposomes, where ensemble methods fall short. Recent improvements in simultaneous multispectral detection and optical design have enhanced reproducibility and resolution, positioning NTA as a cornerstone technique for quantitative characterization across biologics, environmental samples, and industrial nanomaterials. In this talk, we will discuss features of the HORIBA ViewSizer 3000 for various sectors.

Dr. Michaela Laupheimer. DataPhysics, Germany.
Michaela got her PhD from the University of Stuttgart focusing on Physical Chemistry. After joining DataPhysics Instruments she worked in the areas of Technology Transfer gaining a strong background in technologies such as dynamic surface and interface tension measurments, Langmuir Trough, CMC and spinning drop tensiometry amongst others.

Abstract:
Perspectives of Interfacial Chemical Measurements in the Field of EVs studies
This lecture explores the role of interfacial chemical measurements in advancing extracellular vesicle (EV) research. We focus on key techniques that might be of interest to probe the physicochemical properties of EVs at the nanoscale, including the spinning drop, pendant drop, and oscillating drop methods and others . These methods provide insights into membrane mechanics, stability, and interactions with surrounding environments. From ultra-low interfacial tensions analysis, to analysis of interfacial tension and adsorption dynamics, the understanding of these interfacial properties enhances the characterization of EVs.